BDBM395258 N-4-[(4aS,5aS or 4aR,5aR)-5a-Methyl-4-oxo-3-(phenylamino)-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indol-2-yl]pyridin-2-ylacetamide::US10308629, Example 20

SMILES CC(=O)Nc1cc(ccn1)-c1[nH]c2C[C@@]3(C)C[C@H]3C(=O)c2c1Nc1ccccc1

InChI Key InChIKey=YMPIZSLAZWLVSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395258   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395258(US10308629, Example 20 | N-4-[(4aS,5aS or 4aR,5aR)...)
Affinity DataIC50: 36nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent