BDBM395418 (R)-1-((2-(2′-chloro-2-methyl-3′-(3-((2-oxooxazolidin-3-yl)methyl)-1,7-naphthyridin-8-ylamino)biphenyl-3-yl)-7-cyanobenzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid::US10308644, Example 31::US10800768, Example 31::US11339149, Example 31

SMILES Cc1c(cccc1-c1cccc(Nc2nccc3cc(CN4CCOC4=O)cnc23)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(C#N)c2o1

InChI Key InChIKey=KLOWGYQWKMDWLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395418   

LigandPNGBDBM395418((R)-1-((2-(2′-chloro-2-methyl-3′-(3-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395418((R)-1-((2-(2′-chloro-2-methyl-3′-(3-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395418((R)-1-((2-(2′-chloro-2-methyl-3′-(3-((...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent