BDBM395433 (R)-1-((7-chloro-2-(2′-chloro-3′-(4-((1-(hydroxymethyl)cyclobutyl)methylamino)piperidin-1-yl)-2-methylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid::US10308644, Example 46::US10800768, Example 46::US11339149, Example 46

SMILES Cc1c(cccc1-c1cccc(N2CCC(CC2)NCC2(CO)CCC2)c1Cl)-c1nc2cc(CN3CC[C@H](C3)C(O)=O)cc(Cl)c2o1

InChI Key InChIKey=BGWGEYUGCPRZEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395433   

LigandPNGBDBM395433((R)-1-((7-chloro-2-(2′-chloro-3′-(4-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395433((R)-1-((7-chloro-2-(2′-chloro-3′-(4-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent

LigandPNGBDBM395433((R)-1-((7-chloro-2-(2′-chloro-3′-(4-((...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent