BDBM39688 1-(4-(6-((5-chloro-4-((3-(trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-yl)ethyl ketone::US12595236, Compound 49

SMILES CC(C(=O)C(C)N1CCN(c2ccc(Nc3ncc(Cl)c(Nc4cccc(C(F)(F)F)c4)n3)nc2)CC1)N1CCN(c2ccc(Nc3ncc(Cl)c(Nc4cccc(C(F)(F)F)c4)n3)nc2)CC1

InChI Key InChIKey=ZCSYBTSKQYVMGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 39688   

TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 39688BDBM39688(1-(4-(6-((5-chloro-4-((3-(trifluoromethyl)phenyl)a...)
Affinity DataIC50: 308nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2026
Entry Details
US Patent