BDBM397089 2-{5-methyl-2-[5-{[2-(2,2,2- trifluoroethoxy)pyridin-3- yl]carbonyl}hexahydropyrrolo [3,4-c]pyrrol-2(1H)-yl]-1,3- oxazol-4-yl}propan-2-ol::US9987255, 3

SMILES Cc1oc(nc1C(C)(C)O)N1CC2CN(CC2C1)C(=O)c1cccnc1OCC(F)(F)F

InChI Key InChIKey=ATTAFXWKLLYZRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397089   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397089(US9987255, 3 | 2-{5-methyl-2-[5-{[2-(2,2,2- triflu...)
Affinity DataIC50: 106nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397089(US9987255, 3 | 2-{5-methyl-2-[5-{[2-(2,2,2- triflu...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent