BDBM397092 2-(5-methyl-2-{5-[(2- propylphenyl)carbonyl] hexahydropyrrolo[3,4-c] pyrrol-2(1H)-yl}- 1,3-oxazol-4-yl)propan-2-ol::US9987255, 6

SMILES CCCc1ccccc1C(=O)N1CC2CN(CC2C1)c1nc(c(C)o1)C(C)(C)O

InChI Key InChIKey=PZCMZJPMGIPKQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397092   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397092(US9987255, 6 | 2-(5-methyl-2-{5-[(2- propylphenyl)...)
Affinity DataIC50: 32nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397092(US9987255, 6 | 2-(5-methyl-2-{5-[(2- propylphenyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent