BDBM397421 US9987278, Compound Reference 31

SMILES CCCNc1nc(Nc2ccc(cc2)C(N)=O)ncc1C#Cc1cccc(NCCNC(=O)\C=C\CN(C)C)c1

InChI Key InChIKey=VWWLYTLJZDDVDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 397421   

LigandPNGBDBM397421(US9987278, Compound Reference 31)
Affinity DataIC50: 5.5nMAssay Description:Quizartinib (Ambit Biosciences Corporation) was used as Reference Compound 1.6 μL (0.75 ng) of a mutant FLT3 protein (FLT3 D835Y, Life Technolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details
US Patent