BDBM397783 US9994550, Compound 2

SMILES Cc1c(OCCO)n[nH]c1-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N

InChI Key InChIKey=SXHATQMQZUAXRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397783   

TargetFatty acid synthase(Human)
Sagimet Biosciences

US Patent
LigandPNGBDBM397783(US9994550, Compound 2 | US20250017938, Compound 00...)
Affinity DataIC50: 23nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetFatty acid synthase(Human)
Sagimet Biosciences

US Patent
LigandPNGBDBM397783(US9994550, Compound 2 | US20250017938, Compound 00...)
Affinity DataIC50: 23nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details
US Patent