BDBM397900 US9994552, Compound 111

SMILES COc1cc2c(ncnc2cc1OCCN1CCCC1=O)N1CCN(CC1)c1ncc(Cc2ccccc2)cn1

InChI Key InChIKey=FRFZUFZFEJBIKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397900   

TargetMast/stem cell growth factor receptor Kit(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM397900(US9994552, Compound 111)
Affinity DataIC50: 1nMAssay Description:Kit wild type assay: In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM397900(US9994552, Compound 111)
Affinity DataIC50: 5.5nMAssay Description:Kit D816V assay: In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details
US Patent