BDBM398521 US10323020, Example 15::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2,2-dimethylmorpholin-4-yl)pyrimidin-5-yl]methanone

SMILES CC1(C)CN(CCO1)c1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1

InChI Key InChIKey=IBSICRNAULLOEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398521   

TargetAlpha-2C adrenergic receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM398521(US10323020, Example 15 | [4-(3,4-Dihydroisoquinoli...)
Affinity DataIC50: 68nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent