BDBM398782 US10323022, Example 259

SMILES COCC(N1C[C@@H](NC(=O)Nc2c3CCCc3nn2-c2ccccc2)[C@@H](C1)c1ccc(F)c(F)c1)C(=O)OC

InChI Key InChIKey=IRQORBOLDUZQEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398782   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM398782(US10323022, Example 259)
Affinity DataIC50: 100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent