BDBM400216 US10328054, Example Compound 69

SMILES Cc1nc(cs1)C#CC12CC1CN(C2)C(=O)C(C)(C)C

InChI Key InChIKey=SDXHWDHDPNOTOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400216   

TargetMetabotropic glutamate receptor 5(Rat)
Hua Medicine (Shanghai)

US Patent
LigandPNGBDBM400216(US10328054, Example Compound 69)
Affinity DataIC50: 500nMAssay Description:For functional assays, HEK293 cells stably expressing recombinant rat mGluR5 were seeded in 384-well plates and dye loaded using Fluo-8. Cells were t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent