BDBM402110 2-(1-cyanocyclopropyl)-N-{2- [(4-cyanopyridin-2- yl)(methyl)amino]ethyl}-N- ethylbenzamide::US10011595, F-26

SMILES CCN(CCN(C)c1cc(ccn1)C#N)C(=O)c1ccccc1C1(CC1)C#N

InChI Key InChIKey=ROKJYGISQPVREE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402110   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402110(US10011595, F-26 | 2-(1-cyanocyclopropyl)-N-{2- [(...)
Affinity DataIC50: 18.9nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402110(US10011595, F-26 | 2-(1-cyanocyclopropyl)-N-{2- [(...)
Affinity DataIC50: 7.71E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent