BDBM402114 N-{2-[(4-cyanopyridin-2- yl)(methyl)amino]ethyl}-N- ethyl-5-fluoro-2-(2H-1,2,3- triazol-2-yl)benzamide::US10011595, F-30

SMILES CCN(CCN(C)c1cc(ccn1)C#N)C(=O)c1cc(F)ccc1-n1nccn1

InChI Key InChIKey=SBMSLYQANOITJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402114   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402114(US10011595, F-30 | N-{2-[(4-cyanopyridin-2- yl)(me...)
Affinity DataIC50: 24.4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402114(US10011595, F-30 | N-{2-[(4-cyanopyridin-2- yl)(me...)
Affinity DataIC50: 9.44E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent