BDBM402142 N-ethyl-N-(2-((4-(2- hydroxypropan-2- yl)pyrimidin-2- yl)(methyl)amino)ethyl)-3- phenylpicolinamide::US10011595, H-31

SMILES CCN(CCN(C)c1nccc(n1)C(C)(C)O)C(=O)c1ncccc1-c1ccccc1

InChI Key InChIKey=XTJVFLLXMZCHNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402142   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402142(US10011595, H-31 | N-ethyl-N-(2-((4-(2- hydroxypro...)
Affinity DataIC50: 23nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402142(US10011595, H-31 | N-ethyl-N-(2-((4-(2- hydroxypro...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent