BDBM403430 US10335392, Example 37::rac-(3aR,10S,10aS)—N-(tert-butyl)-7-(6-methoxypyridin-3-yl)-10-phenyl-3,3a,10,10a-tetrahydrobenzo[d]pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]imidazole-2(1H)-carboxamide

SMILES CC(C)(C)NC(=O)N1C[C@H]2[C@@H](C1)c1nc3ccc(cc3n1[C@H]2c1ccccc1)-c1ccc(CO)nc1

InChI Key InChIKey=FNKOWPOKUGRHOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 403430   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM403430(US10335392, Example 37 | rac-(3aR,10S,10aS)—N...)
Affinity DataIC50: 5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (LABCYTE, Cat. # LP-0200) at final concentrations ranging from 0.004 μM to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent