BDBM405480 USRE47493, Example 58.6

SMILES CS(O)(O)c1cc(ccc1C1N(CC2CCOCC2)C(=O)N(C2=C1C(=O)CCC2)c1cccc(c1)C(F)(F)F)C#N

InChI Key InChIKey=ALVRQLADJKWHQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 405480   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM405480(USRE47493, Example 58.6)
Affinity DataIC50: 1nMAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat.No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bache...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
US Patent