BDBM405604 US10351547, Compound 2-18::US10597377, Compound 2-218

SMILES CCNCC1CN(C1)c1c(cnc2ccc(cc12)-c1cc(F)cc(C#N)c1O)-c1cc(C)cc(F)c1

InChI Key InChIKey=RXYSZCNRMWNYGP-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 405604   

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM405604(US10351547, Compound 2-18 | US10597377, Compound 2...)
Affinity DataEC50: <10nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC # CCL-61) stably expressing the human SSTR2 are plated in each well of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM405604(US10351547, Compound 2-18 | US10597377, Compound 2...)
Affinity DataEC50: <10nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC # CCL-61) stably expressing the human SSTR2 are plated in each well of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM405604(US10351547, Compound 2-18 | US10597377, Compound 2...)
Affinity DataEC50: <10nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human SSTR2 are plated in each well of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
US Patent