BDBM406222 5-chloro-2-oxo-1,2-dihydroquinolin-3-yl 4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylate::US10336724, Compound 18

SMILES Clc1ccc(CCc2c[nH]c(c2)C(=O)Oc2cc3c(Cl)cccc3[nH]c2=O)cc1

InChI Key InChIKey=NUVCWMVBQMUMGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406222   

TargetD-amino-acid oxidase(Human)
SyneuRx International (Taiwan)

US Patent
LigandPNGBDBM406222(5-chloro-2-oxo-1,2-dihydroquinolin-3-yl 4-(4-chlor...)
Affinity DataIC50: 300nMAssay Description:The hDAAO (human DAAO) activity was measured by using D-serine as a substrate to produce H2O2. The produced H2O2 would be oxidized by peroxidase, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetD-amino-acid oxidase(Pig)
SyneuRx International (Taiwan)

US Patent
LigandPNGBDBM406222(5-chloro-2-oxo-1,2-dihydroquinolin-3-yl 4-(4-chlor...)
Affinity DataIC50: 5.50E+3nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent