BDBM406231 6-(3,5-difluorophenethyl)-3-oxo-2,3-dihydropyridazin-4-yl 4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylate::US10336724, Compound 56

SMILES Fc1cc(F)cc(CCc2cc(OC(=O)c3cc(CCc4ccc(Cl)cc4)c[nH]3)c(=O)[nH]n2)c1

InChI Key InChIKey=RFWWBHSBBNJRAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406231   

TargetD-amino-acid oxidase(Human)
SyneuRx International (Taiwan)

US Patent
LigandPNGBDBM406231(6-(3,5-difluorophenethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 5.50E+3nMAssay Description:The hDAAO (human DAAO) activity was measured by using D-serine as a substrate to produce H2O2. The produced H2O2 would be oxidized by peroxidase, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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TargetD-amino-acid oxidase(Pig)
SyneuRx International (Taiwan)

US Patent
LigandPNGBDBM406231(6-(3,5-difluorophenethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 5.50E+4nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent