BDBM406234 6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridazin-4-yl 3-(4-fluorophenethyl)-1H-pyrazole-5-carboxylate::US10336724, Compound 72

SMILES Fc1ccc(CCc2cc([nH]n2)C(=O)Oc2cc(Cc3cccc4ccccc34)n[nH]c2=O)cc1

InChI Key InChIKey=RYUZIOFOZWQHRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406234   

TargetD-amino-acid oxidase(Human)
SyneuRx International (Taiwan)

US Patent
LigandPNGBDBM406234(6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 300nMAssay Description:The hDAAO (human DAAO) activity was measured by using D-serine as a substrate to produce H2O2. The produced H2O2 would be oxidized by peroxidase, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Pig)
SyneuRx International (Taiwan)

US Patent
LigandPNGBDBM406234(6-(naphthalen-1-ylmethyl)-3-oxo-2,3-dihydropyridaz...)
Affinity DataIC50: 55nMAssay Description:The pkDAAO (porcine kidney DAAO) activity was measured by using D-Proine as a substrate to produce hydrogen peroxide (H2O2). The produced H2O2 would ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent