BDBM406372 N-(Cyclopropylsulfonyl)-4-fluoro-2-((3S,4R or 3R,4S)-4-hydroxy-3-(pyridin-2-ylmethyl)chroman-7-yl)benzamide::US10336733, Example 16

SMILES O[C@@H]1[C@@H](Cc2ccccn2)COc2cc(ccc12)-c1cc(F)ccc1C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=LEINTYMZNNMVKX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406372   

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandPNGBDBM406372(N-(Cyclopropylsulfonyl)-4-fluoro-2-((3S,4R or 3R,4...)
Affinity DataEC50:  4nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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