BDBM406385 2-((Rac-trans)-4-Hydroxy-3-((5-methyl-1,3,4-thiadiazol-2-yl)methyl)chroman-7-yl)-N-((1-methylcyclopropyl)sulfonyl)benzamide::US10336733, Example 29

SMILES Cc1nnc(C[C@H]2COc3cc(ccc3[C@@H]2O)-c2ccccc2C(=O)NS(=O)(=O)C2(C)CC2)s1

InChI Key InChIKey=INDBHAAQBHOODW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406385   

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandPNGBDBM406385(2-((Rac-trans)-4-Hydroxy-3-((5-methyl-1,3,4-thiadi...)
Affinity DataEC50:  740nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
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