BDBM408505 (2S,5R)-5-(2-chlorophenyl)-1-(3-methoxy-5-(2-methoxyethoxy)benzoyl)pyrrolidine-2-carboxylic acid::US10358416, Compound 31::US10781171, Compound 31::US11072582, Compound 31

SMILES COCCOc1cc(OC)cc(c1)C(=O)N1[C@@H](CC[C@@H]1c1ccccc1Cl)C(O)=O

InChI Key InChIKey=POBPCXGVKGASKS-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 408505   

TargetFree fatty acid receptor 2(Human)
Epics Therapeutics

US Patent
LigandPNGBDBM408505(US10358416, Compound 31 | (2S,5R)-5-(2-chloropheny...)
Affinity DataEC50: >1.00E+3nMAssay Description:The assay was used to determine the activity of the compounds of the invention.The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2021
Entry Details
Go to US Patent

TargetFree fatty acid receptor 2(Human)
Epics Therapeutics

US Patent
LigandPNGBDBM408505(US10358416, Compound 31 | (2S,5R)-5-(2-chloropheny...)
Affinity DataEC50: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent

TargetFree fatty acid receptor 2(Human)
Epics Therapeutics

US Patent
LigandPNGBDBM408505(US10358416, Compound 31 | (2S,5R)-5-(2-chloropheny...)
Affinity DataEC50: >1.00E+3nMAssay Description:The assay was used to determine the activity of the compounds of the invention. The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
Go to US Patent