BDBM408895 Methyl 1-(N-((2-cyano-4'-methoxy-3'- methyl- [1,1'-biphenyl]-4-yl)methyl)-3,3- dimethylbutanamido) isoquinoline-6-carboxylate::US10377717, Compound 26

SMILES COC(=O)c1ccc2c(nccc2c1)N(Cc1ccc(-c2ccc(OC)c(C)c2)c(c1)C#N)C(=O)CC(C)(C)C

InChI Key InChIKey=ASQSPCXIKMUPOK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408895   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408895(Methyl 1-(N-((2-cyano-4'-methoxy-3'- methyl- [1,1'...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent