BDBM408936 Methyl 1-(trans-N- ((3'-chloro-4'-methoxy-[1,1'- biphenyl]-4-yl)methyl)-4- hydroxycyclohexanecarboxamido) isoquinoline-6- carboxylate::US10377717, Compound 66

SMILES COC(=O)c1ccc2c(nccc2c1)N(Cc1ccc(cc1)-c1ccc(OC)c(Cl)c1)C(=O)[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=NZHZITJWPPVVDT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408936   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM408936(Methyl 1-(trans-N- ((3'-chloro-4'-methoxy-[1,1'- b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent