BDBM409735 2-[3-Chloro-6-(5-chloro-4-methyl-2-thienyl)pyrrolo[3,2-b]pyridin-::US10377753, Example 602

SMILES CN(C)C(=O)Cn1cc(Cl)c2ncc(cc12)-c1cc(C)c(Cl)s1

InChI Key InChIKey=AYRXUZJFVMEMDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409735   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409735(2-[3-Chloro-6-(5-chloro-4-methyl-2-thienyl)pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent