BDBM410091 N-(Cyclopropylsulfonyl)-2-((rac-trans)-4-hydroxy-3-((5-(thiazol-5-yl)pyridin-2-yl)methyl)chroman-7-yl)benzamide::US10370368, Example 8

SMILES O[C@@H]1[C@@H](Cc2ccc(cn2)-c2cncs2)COc2cc(ccc12)-c1ccccc1C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=QWXGBFFMDWXNHG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410091   

TargetLeukotriene B4 receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410091(N-(Cyclopropylsulfonyl)-2-((rac-trans)-4-hydroxy-3...)
Affinity DataEC50:  12nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent