BDBM41079 (3Z)-3-(1H-imidazol-5-ylmethylene)oxindole::(3Z)-3-(1H-imidazol-5-ylmethylidene)-1H-indol-2-one::3-(1H-imidazol-5-ylmethylene)-1,3-dihydro-2H-indol-2-one::MLS000327715::SMR000180717::cid_5714572

SMILES O=C1Nc2ccccc2C1=Cc1cnc[nH]1

InChI Key InChIKey=VEEGZPWAAPPXRB-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 41079   

TargetSerine/threonine-protein kinase tousled-like 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM41079(SMR000180717 | 3-(1H-imidazol-5-ylmethylene)-1,3-d...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM41079(SMR000180717 | 3-(1H-imidazol-5-ylmethylene)-1,3-d...)
Affinity DataIC50: 2.87E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41079(SMR000180717 | 3-(1H-imidazol-5-ylmethylene)-1,3-d...)
Affinity DataEC50:  2.99E+3nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase 33(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41079(SMR000180717 | 3-(1H-imidazol-5-ylmethylene)-1,3-d...)
Affinity DataEC50:  7.94E+3nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetProtein-tyrosine kinase 2-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM41079(SMR000180717 | 3-(1H-imidazol-5-ylmethylene)-1,3-d...)
Affinity DataIC50: 8.78E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41079(SMR000180717 | 3-(1H-imidazol-5-ylmethylene)-1,3-d...)
Affinity DataEC50:  1.76E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay