BDBM410818 3,5-Dichloro-N-(6-chloro-4-o-tolyl-pyridin-3-yl)-N-methyl-benzamide::US10385022, Example 13

SMILES CN(C(=O)c1cc(Cl)cc(Cl)c1)c1cnc(Cl)cc1-c1ccccc1C

InChI Key InChIKey=HXKMMMJTXBKXHD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410818   

TargetG-protein coupled bile acid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM410818(3,5-Dichloro-N-(6-chloro-4-o-tolyl-pyridin-3-yl)-N...)
Affinity DataEC50:  580nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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