BDBM412145 US10392405, Compound Id 1.009::US11691985, Compound 1.009

SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1

InChI Key InChIKey=BNANEMNUOZTKSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412145   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412145(US10392405, Compound Id 1.009 | US11691985, Compou...)
Affinity DataIC50: 200nMAssay Description:Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM412145(US10392405, Compound Id 1.009 | US11691985, Compou...)
Affinity DataIC50: 1.03E+4nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/20/2020
Entry Details
Go to US Patent