BDBM413579 (2 S)-1-[(2S)-2-[acetyl(methyl)amino]-3-phenyl-propanoyl]-N-[(1S)-1-[[(1S)-3-[(3,5-difluorobenzoyl)amino]-1-(hydroxycarbamoyl)propyl]carbamoyl]-2-methyl-butyl]-N-methyl-pyrrolidine-2-carboxamide::US10414797, Example 11
SMILES CCC(C)[C@H](N(C)C(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)N(C)C(C)=O)C(=O)N[C@@H](CCNC(=O)c1cc(F)cc(F)c1)C(=O)NO
InChI Key InChIKey=AVBFGPRDUCGJRR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 413579
Affinity DataIC50: 174nMAssay Description:MMP-2: Recombinant MMP-2 expressed in Chinese hamster ovary (CHO) cells was obtained from Merck-Millipore (catalog number PF023-5UG). DQ gelatin from...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 71nMAssay Description:MMP-9: Recombinant MMP-9 expressed was obtained from Merck-Millipore (catalog number PF140-5UG, used in examples 1 to 9 and comparative examples) and...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 9.13E+6nMAssay Description:MMP-1:MMP-1 peptide substrate was provided as a stock solution in DMSO (6 mM). For the assay, the substrate was diluted 1× reaction buffer to a conce...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.00E+8nMAssay Description:MMP-3: Preparation of the MMP-3 for the activity assay: MMP-3 was provided as a stock solution (0.1 mg/mL). The enzyme was diluted in water to a fina...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 2.01E+7nMAssay Description:MMP-7: Recombinant MMP-7 expressed in E. Coli was obtained from Merck-Millipore (catalog number 44270). Mca-PLGL-Dpa-AR-NH2 (fluorogenic peptide subs...More data for this Ligand-Target Pair
Ligand InfoSimilars