BDBM413587 (2S)-1-[(2S)-2-acetamido-5-amino-5-oxo-pentanoyl]-N-[(1S)-1-(hydroxycarbamoyl)-2-methyl-butyl]pyrrolidine-2-carboxamide::US10414797, Comparative Example 19::US10414797, Example C19

SMILES CCC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)NO

InChI Key InChIKey=FOFKHQCPPHMUSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413587   

TargetMetalloproteinase inhibitor 2(Long-tailed dwarf hamster)
Iproteos

US Patent
LigandPNGBDBM413587(US10414797, Comparative Example 19 | (2S)-1-[(2S)-...)
Affinity DataIC50: 2.00E+6nMAssay Description:MMP-2: Recombinant MMP-2 expressed in Chinese hamster ovary (CHO) cells was obtained from Merck-Millipore (catalog number PF023-5UG). DQ gelatin from...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/2/2020
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
Iproteos

US Patent
LigandPNGBDBM413587(US10414797, Comparative Example 19 | (2S)-1-[(2S)-...)
Affinity DataIC50: 2.00E+6nMAssay Description:MMP-9: Recombinant MMP-9 expressed was obtained from Merck-Millipore (catalog number PF140-5UG, used in examples 1 to 9 and comparative examples) and...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/2/2020
Entry Details
Go to US Patent