BDBM414066 US10421765, Example 54::US10745420, Example 56

SMILES CCOc1cc(N2Cc3c(C[C@H]2C)ncnc3C2CCN(CC2)S(C)(=O)=O)c2cc[nH]c2n1

InChI Key InChIKey=LSWWTQWUBAIAOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 414066   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414066(US10421765, Example 54 | US10745420, Example 56)
Affinity DataIC50: 123nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414066(US10421765, Example 54 | US10745420, Example 56)
Affinity DataIC50: 123nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414066(US10421765, Example 54 | US10745420, Example 56)
Affinity DataIC50: 773nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent