BDBM41489 (4Z)-2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)methylene]-2-oxazolin-5-one::(4Z)-2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)methylidene]-1,3-oxazol-5-one::(4Z)-2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)methylidene]-5-oxazolone::2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)methylene]-1,3-oxazol-5(4H)-one::MLS000531355::SMR000136333::cid_5646019

SMILES Cc1[nH]c2ccccc2c1\C=C1/N=C(OC1=O)c1ccc(F)cc1

InChI Key InChIKey=CZQAPMORQUMWEO-UHFFFAOYSA-N

Data  2 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 41489   

TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataIC50: 1.93E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  5.53E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  1.66E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetEndoribonuclease toxin MazF(Escherichia coli (strain K12))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  5.59E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetEphrin type-B receptor 4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataIC50: 7.94E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2011
Entry Details
PCBioAssay
TargetEndoribonuclease toxin MazF(Escherichia coli (strain K12))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41489(2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl)meth...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay