BDBM415590 (4S)-4-[[(2S)-2-[[(E)-3-(3,5-Dichlorophenyl)prop-2-enoyl]amino]-2-phenylacetyl]amino]-2,2-difluoro-5-methyl-3-oxo-N-(2,2,2-trifluoroethyl)hexanamide::US10428108, Example 2

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)\C=C\c1cc(Cl)cc(Cl)c1)c1ccccc1)C(=O)C(F)(F)C(=O)NCC(F)(F)F

InChI Key InChIKey=KOPSBGVCHLGHEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415590   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM415590(US10428108, Example 2 | (4S)-4-[[(2S)-2-[[(E)-3-(3...)
Affinity DataIC50: 40nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent