BDBM41666 MLS000529336::N-(4-aminocarbonylphenyl)oxolane-2-carboxamide::N-(4-carbamoylphenyl)-2-oxolanecarboxamide::N-(4-carbamoylphenyl)oxolane-2-carboxamide::N-(4-carbamoylphenyl)tetrahydrofuran-2-carboxamide::SMR000121811::Tetrahydro-furan-2-carboxylic acid (4-carbamoyl-phenyl)-amide::cid_3155148

SMILES Cc1cc(N2CCOC[C@@H]2C(F)(F)F)cc(F)c1C(=O)N[C@@H](Cc1ccc(-n2c(=O)[nH]c3cnccc3c2=O)c2ncccc12)C(=O)O

InChI Key InChIKey=FSZYBIFIACXSAG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 41666   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 41666BDBM41666(US11116760, Example 421)
Affinity DataEC50:  0.191nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent