BDBM417711 2-(6-{5-bromo-2- [(oxan-4- yl)amino]pyrimidiin-4- yl}-1-oxo-2,3-dihydro- 1H-isoindol-2-yl)-N- [(1S,2S)-2-hydroxy-1- phenylpropyl] acetamide::US10457669, Example 336

SMILES C[C@H](O)[C@@H](NC(=O)CN1Cc2ccc(cc2C1=O)-c1nc(NC2CCOCC2)ncc1Br)c1ccccc1

InChI Key InChIKey=ZBSCYCHKBUEGHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 417711   

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417711(2-(6-{5-bromo-2- [(oxan-4- yl)amino]pyrimidiin-4- ...)
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent