BDBM41846 (2-nitro-5-piperazino-phenyl)-(tetrahydrofurfuryl)amine::2-nitro-5-(1-piperazinyl)-N-(tetrahydro-2-furanylmethyl)aniline::2-nitro-N-(2-oxolanylmethyl)-5-(1-piperazinyl)aniline::2-nitro-N-(oxolan-2-ylmethyl)-5-piperazin-1-yl-aniline::2-nitro-N-(oxolan-2-ylmethyl)-5-piperazin-1-ylaniline::MLS000576313::SMR000197953::cid_2933906

SMILES [O-][N+](=O)c1ccc(cc1NCC1CCCO1)N1CCNCC1

InChI Key InChIKey=NBQUAKXLTFLOAI-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 41846   

TargetSerine/threonine-protein kinase PLK1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41846(cid_2933906 | 2-nitro-N-(2-oxolanylmethyl)-5-(1-pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase PLK1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41846(cid_2933906 | 2-nitro-N-(2-oxolanylmethyl)-5-(1-pi...)
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase PLK1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41846(cid_2933906 | 2-nitro-N-(2-oxolanylmethyl)-5-(1-pi...)
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM41846(cid_2933906 | 2-nitro-N-(2-oxolanylmethyl)-5-(1-pi...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay