BDBM42010 3-[4-[4-(2-hydroxyphenyl)-1-piperazinyl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one::3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxidanylidene-butyl]-2-sulfanylidene-1H-quinazolin-4-one::3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxobutyl]-2-sulfanylidene-1H-quinazolin-4-one::3-[4-[4-(2-hydroxyphenyl)piperazino]-4-keto-butyl]-2-thioxo-1H-quinazolin-4-one::AS-920-37a::US20240208944, Compound 43::cid_24178258

SMILES Oc1ccccc1N1CCN(CC1)C(=O)CCCn1c(=S)[nH]c2ccccc2c1=O

InChI Key InChIKey=UKKJAWDABGCVEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 42010   

TargetEstrogen receptor(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM42010(3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxidany...)
Affinity DataIC50: 70nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetCytochrome b-245 heavy chain(Human)
Emory University

US Patent
LigandPNGBDBM42010(3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxidany...)
Affinity DataIC50: 2.30E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetNADPH oxidase 4(Human)
Emory University

US Patent
LigandPNGBDBM42010(3-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]-4-oxidany...)
Affinity DataIC50: 5.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent