BDBM422020 US10494380, Compound I-156::US10494380, Compound I-260

SMILES COc1cnc(nc1)N1CCn2c(C)cc3c(-c4ccc(Cl)cc4)c([C@H](OC(C)(C)C)C(O)=O)c(C)c1c23

InChI Key InChIKey=FJNYLBFJLMFXHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 422020   

TargetCytochrome P450 2C9(Human)
Shionogi

US Patent
LigandPNGBDBM422020(US10494380, Compound I-260 | US10494380, Compound ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Each five kinds of substrates, human hepatic microsome, and a test drug in 50 mmol/L Hepes buffer as a reaction solution was added to a 96-well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Shionogi

US Patent
LigandPNGBDBM422020(US10494380, Compound I-260 | US10494380, Compound ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Each five kinds of substrates, human hepatic microsome, and a test drug in 50 mmol/L Hepes buffer as a reaction solution was added to a 96-well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
Go to US Patent