BDBM42267 2-[2-(benzotriazol-1-yl)ethanoyl-prop-2-enyl-amino]-2-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)ethanamide::2-[Allyl-(2-benzotriazol-1-yl-acetyl)-amino]-2-(2,4-dimethoxy-phenyl)-N-(2-methoxy-ethyl)-acetamide::2-[[2-(1-benzotriazolyl)-1-oxoethyl]-prop-2-enylamino]-2-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)acetamide::2-[[2-(benzotriazol-1-yl)acetyl]-prop-2-enylamino]-2-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)acetamide::2-[allyl-[2-(benzotriazol-1-yl)acetyl]amino]-2-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)acetamide::MLS000031807::SMR000005235::cid_645363

SMILES N1(C=NC=C1)C1=CC=C(C=N1)/C=C/C=1C=NC(=NC1)N1[C@H](CN(CC1)C=1C=NC(=CC1)F)COC

InChI Key InChIKey=UPDGKKWDZRYOHL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42267   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42267BDBM42267((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  0.900nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584

TargetAmyloid-beta precursor protein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42267BDBM42267((R,E)-5-(2-(6-(1H-imidazol-1-yl)pyridin-3-yl)vinyl...)
Affinity DataKi:  1.20E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584