BDBM42289 1-(4-Methoxy-benzyl)-3,3-dimethyl-1-(8-methyl-2-oxo-1,2-dihydro-quinolin-3-ylmethyl)-urea::1-[(2-keto-8-methyl-1H-quinolin-3-yl)methyl]-3,3-dimethyl-1-p-anisyl-urea::1-[(4-methoxyphenyl)methyl]-3,3-dimethyl-1-[(8-methyl-2-oxidanylidene-1H-quinolin-3-yl)methyl]urea::1-[(4-methoxyphenyl)methyl]-3,3-dimethyl-1-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]urea::MLS000074000::SMR000006092::cid_654410

SMILES FCCOC[C@@H]1N(CCN(C1)C1=NC=C(C=N1)C#CC=1C=NC(=CC1)C=1C=NN(C1)C)C1=NC=NC=N1

InChI Key InChIKey=LQKMOHMFSKCWFP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42289   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42289BDBM42289((R)-2-(2-((2-fluoroethoxy)methyl)-4-(5-((6-(1-meth...)
Affinity DataKi:  0.449nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584

TargetAmyloid-beta precursor protein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42289BDBM42289((R)-2-(2-((2-fluoroethoxy)methyl)-4-(5-((6-(1-meth...)
Affinity DataKi:  1.20E+3nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584