BDBM42321 4-hydroxy-2-keto-3-(3-methoxyphenyl)-N-piperonyl-1H-quinazoline-4-carboxamide::MLS000044406::N-(1,3-benzodioxol-5-ylmethyl)-3-(3-methoxyphenyl)-4-oxidanyl-2-oxidanylidene-1H-quinazoline-4-carboxamide::N-(1,3-benzodioxol-5-ylmethyl)-4-hydroxy-3-(3-methoxyphenyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carboxamide::N-(1,3-benzodioxol-5-ylmethyl)-4-hydroxy-3-(3-methoxyphenyl)-2-oxo-1H-quinazoline-4-carboxamide::SMR000022183::cid_3237045

SMILES N=1N(N=CC1)C1CCN(CC1)C1=CC=C(C=N1)C#CC=1C=NC(=NC1)N1C[C@@H](N(CC1)C1=NC=CC=N1)COC

InChI Key InChIKey=JATGXQNRXIMVFM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 42321   

TargetAlpha-synuclein(Human)
8932 Hightail Drive

WIPO
LigandChemical structure of BindingDB Monomer ID 42321BDBM42321((R)-5-((6-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl...)
Affinity DataKi:  1.15nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584