BDBM423228 4-methoxy-6-(4- (((3S,5R)-3-methyl- 5-(4-methyl-1-oxo- 1,3- dihydroisobenzofur- an-5-yl)piperazin- 1-yl)methyl)-2H- 1,2,3-triazol-2- yl)nicotinonitrile::US10501449, Example 107-I

SMILES COc1cc(ncc1C#N)-n1ncc(CN2C[C@H](C)N[C@@H](C2)c2ccc3C(=O)OCc3c2C)n1

InChI Key InChIKey=XOZAQPATCSISQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423228   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423228(US10501449, Example 107-I | 4-methoxy-6-(4- (((3S,...)
Affinity DataIC50: 18nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent