BDBM423246 3-methyl-4-(((3S,5R)- 3-methyl-5-(4-methyl- 1-oxo-1,3- dihdyroisobenzofuran- 5-yl)piperazin-1- yl)methyl)-1-(2- methylpyrimidin-4-yl)- 1,3-dihydro-2H- imidazol-2-one::US10501449, Example 173-I

SMILES C[C@H]1CN(Cc2cn(-c3ccnc(C)n3)c(=O)n2C)C[C@H](N1)c1ccc2C(=O)OCc2c1C

InChI Key InChIKey=NYRDYSLMHINUTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423246   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423246(3-methyl-4-(((3S,5R)- 3-methyl-5-(4-methyl- 1-oxo-...)
Affinity DataIC50: 21nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent