BDBM42445 5-tert-butyl-N-[2-(cyclopentylamino)-2-keto-ethyl]-N-(2-methoxyphenyl)-3-methyl-2-furamide::5-tert-butyl-N-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-(2-methoxyphenyl)-3-methyl-furan-2-carboxamide::5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-methoxyphenyl)-3-methyl-2-furancarboxamide::5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-methoxyphenyl)-3-methylfuran-2-carboxamide::MLS000764944::SMR000286749::cid_1454987

SMILES C=CC(=O)N1CCc2nn(-c3ccc(C4CCC4)c(O)c3)c3c2C(C1)N(C(=O)c1cnc(C(F)(F)F)c(O)c1)CC3

InChI Key InChIKey=UMVIEUMWWMRESW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42445   

LigandChemical structure of BindingDB Monomer ID 42445BDBM42445(1-(2-(4-cyclobutyl-3- hydroxyphenyl)-5-(5- hydroxy...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 42445BDBM42445(1-(2-(4-cyclobutyl-3- hydroxyphenyl)-5-(5- hydroxy...)
Affinity DataIC50: 10nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details
US Patent