BDBM425207 4-[3-[dicyclopropyl- (4-fluorophenyl)methyl]- 1H-pyrrolo[2,3-b] pyridin-5-yl]-3,5- dimethyl-isoxazole::US10519177, Compound P-0085

SMILES Cc1noc(C)c1-c1cnc2[nH]cc(c2c1)C(C1CC1)(C1CC1)c1ccc(F)cc1

InChI Key InChIKey=GZXZSNKBLOMXFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425207   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425207(US10519177, Compound P-0085 | 4-[3-[dicyclopropyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent