BDBM425227 4-[1-cyclopentylsulfonyl- 3-(2-methoxypyrimidin- 5-yl)pyrrolo[3,2-b] pyridin-6-yl]-3,5- dimethyl-isoxazole::US10519177, Compound P-0105

SMILES COc1ncc(cn1)-c1cn(c2cc(cnc12)-c1c(C)noc1C)S(=O)(=O)C1CCCC1

InChI Key InChIKey=NSOOFTKXJIKCEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425227   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425227(US10519177, Compound P-0105 | 4-[1-cyclopentylsulf...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent