BDBM425238 4-[[5-(3,5- dimethylisoxazol-4-yl)-1- methyl-pyrrolo[2,3- b]pyridin-3-yl]methyl]-N- ethyl-piperidine-1- carboxamide::US10519177, Compound P-0117

SMILES CCNC(=O)N1CCC(Cc2cn(C)c3ncc(cc23)-c2c(C)noc2C)CC1

InChI Key InChIKey=AMNKGTDYRCBGFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425238   

TargetBromodomain-containing protein 4 [44-164](Human)
Plexxikon

US Patent
LigandPNGBDBM425238(US10519177, Compound P-0117 | 4-[[5-(3,5- dimethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2020
Entry Details
US Patent